Director of Research & Development

Dr Cindy Li

Immunologist and translational researcher driving cellular therapy innovation at Biosceptre — pioneering the BRiDGECAR™ universal CAR-T system to transform cancer treatment.

Dr Cindy Li

About

Dr Cindy Li studied medicine at Zhejiang University and worked as a trainee physician in a comprehensive oncology centre, before completing a PhD in Immunology and Haematology at the University of Sydney.

Her research has focused on the development of cellular therapies, with extensive experience in clinical grade CAR-T production and GMP compliant T cell therapy and cord blood unit production.

Dr Li also acts as a scientific consultant to an Australian human research ethics committee.

Research & Expertise

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CAR-T Cell Therapy

Clinical grade CAR-T production targeting nfP2X7 — a cancer-specific biomarker expressed across most solid and liquid tumours.

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BRiDGECAR™ Platform

Pioneering Biosceptre's universal CAR-T system combining nfP2X7-targeted CAR-T with multiple targeted antibodies.

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GMP Manufacturing

GMP compliant cell therapy and cord blood unit production meeting regulatory standards for clinical trials.

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Translational Research

Bridging laboratory discoveries to clinical applications — from pre-clinical validation to Phase I trials.

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Ethics & Governance

Scientific consultant to an Australian human research ethics committee, ensuring research integrity.

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R&D Leadership

Directing research strategy across multiple oncology programs targeting liquid and solid tumours.

Journey

2022 – Present

Director of Research & Development

Biosceptre

Leading R&D strategy for Biosceptre's BRiDGECAR™ system — a multiple-targeted universal CAR-T platform with the potential to treat most forms of cancer. Overseeing programs targeting liquid and solid tumours, working alongside a world-class advisory board including a Nobel Laureate.

PhD

Doctor of Philosophy — Immunology & Haematology

University of Sydney

Research focused on cellular therapies, with extensive experience in clinical grade CAR-T production and GMP compliant T cell therapy and cord blood unit production.

MBBS

Medicine (MBBS)

Zhejiang University

Medical degree with clinical training as a trainee physician in a comprehensive oncology centre, providing foundational understanding of cancer biology and patient care.

Publications

Selected peer-reviewed publications and research contributions

The Current Landscape of Modular CAR T Cells

Biosceptre (Aust) Pty Ltd., Westmead, NSW, Australia

Int J Mol Sci. 2025;26(24):11898

Development of CAR T Cell Therapy in Children — A Comprehensive Overview

Ziduo Li et al.

J Clin Med. 2022;11(8):2158

Investigation of product-derived lymphoma following infusion of piggyBac-modified CD19 chimeric antigen receptor T cells

Ziduo Li et al.

Blood. 2021;138(16):1391-1405

Prophylactic antigen-specific T-cells targeting seven viral and fungal pathogens after allogeneic haemopoietic stem cell transplant

Ziduo Li et al.

Clin Transl Immunology. 2021;10(3):e1249

Rapidly expanded partially HLA DRB1-matched fungus-specific T cells mediate in vitro and in vivo antifungal activity

Ziduo Li et al.

Blood Adv. 2020;4(14):3443-3456

Targeting CD83 in mantle cell lymphoma with anti-human CD83 antibody

Ziduo Li et al.

Clin Transl Immunology. 2020;9(7):e1156

CD83: Activation Marker for Antigen Presenting Cells and Its Therapeutic Potential

Ziduo Li, X Ju, PA Silveira, E Abadir, M-H Hsu, D Hart, GJ Clark

Front Immunol. 2019;10:1312

CD83 is a new potential biomarker and therapeutic target for Hodgkin lymphoma

Ziduo Li, X Ju, K Lee, C Clarke, JL Hsu, E Abadir, CE Bryant, S Pears, N Sunderland, S Heffernan et al.

Haematologica. 2018;103(4):655-665

The Analysis of CD83 Expression on Human Immune Cells Identifies a Unique CD83+-Activated T Cell Population

Ziduo Li et al.

J Immunol. 2016;197(12):4613-4625

A circulating tumor cell cluster-based model for tumor metastasis (Hypothesis)

Ziduo Li et al.

Oncol Lett. 2016;12(6):4891-4895

Get in Touch

Interested in collaboration, consulting, or connecting on research? I'd love to hear from you.